WNT3A Recombinant antibody, PBS Only

WNT3A Uni-rAbTM Recombinant Antibody for IF/ICC, FC (Intra), Indirect ELISA
Cat No. 84577-4-PBS
Clone No.241993E8

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, FC (Intra), Indirect ELISA

241993E8, Protein Wnt 3a, Protein Wnt-3a

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

84577-4-PBS targets WNT3A in IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen WNT3A fusion protein Ag25051 Predict reactive species
Full Name wingless-type MMTV integration site family, member 3A
Calculated Molecular Weight 352 aa, 39 kDa
GenBank Accession NumberBC103921
Gene Symbol WNT3A
Gene ID (NCBI) 89780
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP56704
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

WNT3A belongs to wingless-type MMTV integration site family, and abnormal Wnt signalling is often associated with severe human diseases, including cancer, osteoporosis and other degenerative disorders. WNT3A is a secreted glycoprotein that is involved in both canonical and non-canonical Wnt signaling pathways. The canonical Wnt pathway, also known as the β-catenin-dependent pathway, regulates gene expression by stabilizing β-catenin, which then translocates to the nucleus and interacts with transcription factors like TCF/LEF. It's shown to promote trophectoderm formation in embryonic stem cells. It's reported that the canonical Wnt/β-catenin signaling pathway also contributes to the carcinogenesis and progression of lung cancer cell lines. The non-canonical pathways, which are β-catenin-independent, are involved in cytoskeletal organization and cell polarity.

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