ZNF410 Polyclonal antibody, PBS Only

• 

  WB analysis using 14529-1-AP (same clone as 14529-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14529-1-AP (ZNF410 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14529-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 14529-1-AP (same clone as 14529-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14529-1-AP (ZNF410 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14529-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

ZNF410 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 14529-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

Zinc finger protein APA 1, Zinc finger protein 410, APA1, APA 1, Another partner for ARF 1

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Product Information

14529-1-PBS targets ZNF410 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag6028

  Product name: Recombinant human ZNF410 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-351 aa of BC050683

  Sequence: MLSDELESKPELLVQFVQNTSIPLGQGLVESEAKDITCLSLLPVTEASECSRLMLPDDTTNHSNSSKEVPSSAVLRSLRVNVGPDGEETRAQTVQKSPEFLSTSESSSLLQDLQPSDSTSFILLNLTRAGLGSSAEHLVFVQDEAEDSGNDFLSSESTDSSIPWFLRVQELAHDSLIAATRAQLAKNAKTSSNGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQS

• Full Name: zinc finger protein 410
• Calculated Molecular Weight: 52 kDa
• Observed Molecular Weight: 52-67 kDa
• GenBank Accession Number: BC050683
• Gene Symbol: ZNF410
• Gene ID (NCBI): 57862
• RRID: AB_2257520
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q86VK4
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

ZNF410 (Zinc Finger Protein 410) is a transcription factor involved in the regulation of gene expression, particularly in the context of fetal hemoglobin (HbF) repression and chromatin remodeling. This protein is highly conserved among mammals and plays a crucial role in erythroid cells. The study found that ZNF410 uniquely silences HbF by activating its sole target gene, CHD4, a known HbF repressor in erythroid cells. (PMID: 40158221)