Mouse calreticulin Recombinant antibody, PBS Only

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  WB analysis using 85593-6-RR (same clone as 85593-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85593-6-RR (Calr antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85593-6-PBS in a different storage buffer formulation.

calreticulin Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 85593-6-PBS

Clone No.243011A9

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

Calr, Calregulin, CRP55, Endoplasmic reticulum resident protein 60, ERp60

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Product Information

85593-6-PBS targets calreticulin in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: calreticulin fusion protein Eg3005
• Full Name: calreticulin
• Calculated Molecular Weight: 48 kDa
• Observed Molecular Weight: 50-55 kDa
• GenBank Accession Number: NM_007591.3
• Gene Symbol: Calr
• Gene ID (NCBI): 12317
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P14211
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CALR, also named as grp60, ERp60, HACBP, CRP55, CRTC and Calregulin, belongs to the calreticulin family. It is a molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. CALR is a ER marker. It interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. CALR interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export.