• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human BMP-4 protein- GMP grade


1.5-9 ng/mL

Species Reactivity




ISO 13485 certified HumanKine® human cell-expressed cytokines and growth factors

Cat no : HZ-1045-GMP


BMP 2B, BMP 4, BMP2B, BMP2B1, BMP4, BMP-4, Bone morphogenetic protein 2B, bone morphogenetic protein 4, DVR4, MCOPS6, ZYME

Technical Specifications

GeneID 652
Species Human
Expression HEK293
EC50 1.5-9 ng/mL
Purity >95%
Endotoxin<0.1 EU/µg
Accession NumberP12644
Molecular Mass 20 to 24 kDa reduced, 32 to 38 kDa non-reduced, homodimer, glycosylated
Formulation 2x PBS + 6% Ethanol, See Certificate of Analysis for details
Species Reactivity human,mouse

Stability and Reconstitution

Stability and StorageProduct FormTemperature ConditionsStorage Time
(From Date of Receipt)
Lyophilized-20°C to -80°CUntil Expiry Date
LyophilizedRoom Temperature2 weeks
Reconstituted as per CofA-20°C to -80°C6 months
Reconstituted as per CofA4°C1 week
Avoid repeated freeze-thaw cycles.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein to 0.2 mg/mL in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin (HSA). Gently swirl or tap vial to mix.

GMP Quality Policies

HumanKine® GMP (Good Manufacturing Practice) recombinant proteins are manufactured and validated in accordance with ISO 13485 quality management system and is compliant with GMP.
Our GMP recombinant proteins are animal component free (ACF), xeno free (XF) and tag free (TF). Read more about these policies here.


Bone morphogenetic protein-4 (BMP-4), also known as BMP2B and DVR4, belongs to the TGF-beta family. BMPs have been shown to promote astroglial differentiation both in vitro and in vivo. BMP-4 can also induce cartilage and bone formation (PMID 16234975). Xeno-free Recombinant Human BMP-4 is expressed in human 293 cells as a disulfide linked homodimeric glycoprotein with an apparent molecular mass of 34 kDa.


BMP 2B, BMP 4, BMP2B, BMP2B1, BMP4, BMP-4, Bone morphogenetic protein 2B, bone morphogenetic protein 4, DVR4, MCOPS6, ZYME


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Jose (Verified Customer) (02-09-2024)

Shipping was fast and product as of yet is working well and as needed, You all should look into getting your COAs on the site, and maybe searchable so that if the paper copy is lost you can look up COA by lot number and it will generate the PDF so as not to have to wait for a response from you all.

  • Applications: Cell culture

Xunyu (Verified Customer) (07-26-2022)


  • Applications: Cell culture

Xunyu (Verified Customer) (06-13-2022)


  • Applications: Cell culture