• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human FGF-7 (KGF) protein

Activity

4-20 ng/mL EC50

Species Reactivity

human,monkey

Purity

>95%

Cat no : HZ-1100

Synonyms

FGF 7, FGF7, FGF-7, Fibroblast growth factor 7, HBGF 7, Keratinocyte growth factor, KGF



Technical Specifications

GeneID 2252
Species Human
Expression HEK293
Activity 4-20 ng/mL EC50
Purity >95%
Endotoxin<1 EU/μg
Accession NumberP21781
Molecular Mass 17 and 30 kDa, monomer, glycosylated
Formulation 1x PBS, See Certificate of Analysis for details
Species Reactivity human,monkey

Stability and Reconstitution

Stability and StorageProduct FormTemperature ConditionsStorage Time
(From Date of Receipt)
Lyophilized-20°C to -80°CUntil Expiry Date
LyophilizedRoom Temperature2 weeks
Reconstituted as per CofA-20°C to -80°C6 months
Reconstituted as per CofA4°C1 week
Avoid repeated freeze-thaw cycles.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1x PBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).

Background

Fibroblast growth factor 7 (FGF-7), also known as keratinocyte growth factor (KGF), belongs to the FGF family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion (PMID 11276432, 15863033). FGF-7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes (PMID 15327889).

Synonyms

FGF 7, FGF7, FGF-7, Fibroblast growth factor 7, HBGF 7, Keratinocyte growth factor, KGF

Publications

SpeciesTitle
mouse

Stem Cell Res Ther

Bronchioalveolar stem cells derived from mouse-induced pluripotent stem cells promote airway epithelium regeneration.

Authors - Naoya Kawakita
human

J Invest Dermatol

Increased KGF expression promotes fibroblast activation in a double paracrine manner resulting in cutaneous fibrosis.

Authors - JohannaCanady