Animal-free Recombinant Human FGF-7 (KGF) is expressed in human 293 cells as a monomeric glycoprotein with an apparent molecular mass of 17 and 30 kDa. FGF-7 appears to act on epithelial cells. It also seems to motivate and stimulate proliferation, migration, and differentiation of these cells. It plays a significant role in development, morphogenesis, wound healing, angiogenesis, and tumorigenesis. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. Authentic glycosylation contributes to stability in cell growth media and other applications.

Fibroblast growth factor 7 (FGF-7), also known as keratinocyte growth factor (KGF), belongs to the FGF family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion (PMID 11276432, 15863033). FGF-7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes (PMID 15327889).