ADRP/Perilipin 2 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 15294-1-AP

Featured Product KD/KO validated

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Con: 52 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Transfected HEK-293 cells

Positive IHC detected in:
human liver tissue, human colon cancer tissue, human liver tissue, human liver cancer tissue, human renal cell carcinoma tissue

Positive IF detected in:
Oleic acid treated HeLa cells

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
adipose differentiation-related protein

Calculated molecular weight:
48 kDa

Observed molecular weight:
50-55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ADFP

Synonyms
ADFP, Adipophilin, ADRP, Perilipin 2, PLIN2
Background

ADRP (adipocyte differentiation related protein) also known as ADFP, adipophilin, or perilipin-2, is a member of PAT family which is responsible for the transportation of lipids and the formation of lipid droplets. ADRP is localized on the surface of lipid droplets in a variety of tissues and cell lines. ADRP is not detected in undifferentiated cells but increases rapidly to high levels when adipocyte precursors differentiate into adipocytes. Anti-ADRP antibody is a reliable and sensitive marker for lipid droplet. Enhanced expression of ADRP is linked to diseases with abnormal lipid storage, including hepatic steatosis, atherosclerosis and diabetes. Immunohistochemistry of ADRP may facilitate histomorphological diagnosis of these diseases.


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