Aquaporin 4 Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 16473-1-AP

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Freight/Packing

Con: 60 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse heart tissue, mouse brain tissue, mouse heart tissue, mouse kidney tissue, rat brain tissue, SKOV-3 cells

Positive IP detected in:
mouse heart tissue

Positive IHC detected in:
human brain tissue, human brain tissue, human kidney tissue, mouse heart tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
aquaporin 4

Calculated molecular weight:
323aa,35 kDa

Observed molecular weight:
35-37, 32-34 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AQP4

Synonyms
AQP 4, AQP4, aquaporin 4, NMO-IgG
Background

Aquaporins are specialized water transport channels in plasma membranes of water-permeable tissues. Aquaporin-4 (AQP4) is the most abundant water channel in the human central nervous system and is important to fluid movements in brain. Aquaporin-4 exists as two isoforms, a long (M1) isoform with translation initiation at Met-1, and a shorter (M23) isoform with translation initiation at Met-23, with molecular weights around 35-37 kDa and 32-34 kDa, respectively.


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