B2M Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66207-1-Ig |CloneNo.: 1C3B7

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Con: 219 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Raji cells

Positive IHC detected in:
human prostate cancer tissue, human prostate cancer tissue, human renal cell carcinoma tissue

Recommended dilution:
WB : 1:1000-1:8000
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
beta-2-microglobulin

Calculated molecular weight:
14 kDa

Observed molecular weight:
13 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
B2M

Synonyms
B2M, beta 2 microglobulin, HDCMA22P
Background

Beta-2-microglobulin (B2M) is a component of MHC class I molecules, which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions as a result of shedding from cell surfaces or intracellular release. B2M has various biological functions, including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases.


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