CD45 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60287-1-Ig |CloneNo.: 4E9B2

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Con: 250 μg/150 μl

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Species specificity:
human, pig

Positive WB detected in:
pig spleen tissue, Raji cells

Positive IHC detected in:
human tonsillitis tissue

Positive FC detected in:
Raji cells

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
protein tyrosine phosphatase, receptor type, C

Calculated molecular weight:
1304aa,147 kDa

Observed molecular weight:
220 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PTPRC

Synonyms
B220, CD45, CD45R, GP180, L CA, LCA, Leukocyte common antigen, LY5, PTPRC, RPTPC, T200
Background

CD45, also known as leukocyte common antigen (LCA), B220, and T200, is a 180-240 kD single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 is one of the best negative selection markers for characterizing and/or isolating human mesenchymal stem cells from bone marrow and other sources. Along with the positive selection markers (such as CD29, CD44, CD90, CD105 and CD166), negative selection markers (such as CD34 and CD45) are used for MSC identification.


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