Cryptochrome 1 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 13474-1-AP

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Con: 28 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Y79 cells, rat testis tissue

Positive IHC detected in:
human testis tissue, human breast cancer tissue

Positive IF detected in:
Hela cells, MCF-7 cells

Recommended dilution:
WB : 1:500-1:3000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cryptochrome 1 (photolyase-like)

Calculated molecular weight:
586aa,66 kDa

Observed molecular weight:
70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CRY1

Synonyms
CRY1, Cryptochrome 1, PHLL1
Background

Cryptochrome circadian clock 1 (CRY1) is a flavin adenine dinucleotide-binding protein with MW of 66 kDa. CRY1 is a key component of the circadian core oscillator complex, which regulates the circadian clock. CRY1 predominantly displays evening-time expression and serves as a strong repressor of morning-time elements (E box/E-prime box) when bound to the BMAL1 (ARNTL; 602550)/CLOCK (601851) complex. (PubMed: 21236481)


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