HLA class I (HLA-C) Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 15777-1-AP

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Con: 40 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Jurkat cells, HL-60 cells

Positive IP detected in:
Jurkat cells

Positive IHC detected in:
human lymphoma tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
major histocompatibility complex, class I, C

Calculated molecular weight:
366aa,41 kDa

Observed molecular weight:
44 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
HLA-C

Synonyms
D6S204, FLJ27082, HLA C, HLA Cw, HLA Cw12, HLA JY3, HLAC, HLA-C, HLC C, MHC class I antigen Cw*7, PSORS1
Background

Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). There are two classes of HLA antigens: class I (HLA-A, B and C) and class II (HLA-D). This class I molecules are polymorphic membrane glycoproteins composed of a heavy (alpha) chain (44 kDa) which is encoded by a HLA class I gene (HLA-A, B or C), and β2-microglobulin light (beta) chain (12 kDa). They are involved in the presentation of foreign antigens to the immune system. (PMID: 667938; 3375250)


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