Hsc70 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66442-1-Ig |CloneNo.: 1A4B3

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Con: 150 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells

Positive IHC detected in:
human ovary tumor tissue

Recommended dilution:
WB : 1:3000-1:20000
IHC : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
heat shock 70kDa protein 8

Calculated molecular weight:
70 kDa

Observed molecular weight:
70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
HSPA8

Synonyms
Heat shock 70 kDa protein 8, heat shock 70kDa protein 8, HSC54, Hsc70, HSC71, HSP71, HSP73, HSPA10, HSPA8, LAP1, NIP71
Background

HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson’s disease, indicating its implication in neurodegenerative disease. (21832061)


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