PANX1 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 12595-1-AP

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Con: 21 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
human brain tissue, HeLa cells, human brain tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human kidney tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
pannexin 1

Calculated molecular weight:
426aa,48 kDa

Observed molecular weight:
48kd,98kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PANX1

Synonyms
MRS1, pannexin 1, PANX1, PX1, UNQ2529
Background

PANX1, also named as MRS1, belongs to the pannexin family. It plays a role as a Ca2+-leak channel to regulate ER Ca2+ homeostasis. It is a structural component of the gap junctions and the hemichannels. PANX1 induced the formation of intercellular channels with characteristics of gap junctions. PANX1 is 48-kDa protein which contains 4 transmembrane domains and cytoplasmic N and C termini. It is a mediator of find-me signal/nucleotide release from apoptotic cells.


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