AP5Z1/SPG48 Monoclonal antibody, PBS Only

AP5Z1/SPG48 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 66533-1-PBS
Clone No.1G1D7

Host / Isotype

Mouse / IgG1

Reactivity

Human, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

AP-5 complex subunit zeta-1, AP5Z1, AP5Z1/SPG48, KIAA0415, SPG48, Zeta5

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

66533-1-PBS targets AP5Z1/SPG48 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human, rat samples.

Tested Reactivity Human, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen AP5Z1/SPG48 fusion protein Ag26961 Predict reactive species
Full Name KIAA0415
Calculated Molecular Weight 807 aa, 88 kDa
Observed Molecular Weight 88 kDa, 160 kDa
GenBank Accession NumberBC037399
Gene Symbol AP5Z1/SPG48
Gene ID (NCBI) 9907
RRIDAB_2881896
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDO43299
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

AP5Z1, also known as SPG48 and KIAA0415, is a part of AP-5. Biallelic mutations in the AP5Z1 gene encoding the AP5Z1 subunit have been described in a small number of patients with hereditary spastic paraplegia (HSP). AP5Z1 physically interacts with other HSP proteins and that patient cells are sensitive to DNA damaging drugs.

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