BMPR2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 19087-1-AP

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Freight/Packing

Con: 55 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human heart tissue, mouse brain tissue

Positive IP detected in:
mouse brain tissue

Positive FC detected in:
PC-3 cells

Recommended dilution:
WB : 1:1000-1:6000
IP : 0.5-4.0 ug for IP and 1:500-1:3000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
bone morphogenetic protein receptor, type II (serine/threonine kinase)

Calculated molecular weight:
115 kDa

Observed molecular weight:
120 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BMPR2

Synonyms
BMP type 2 receptor, BMP type II receptor, BMPR 2, BMPR II, BMPR2, BMPR3, BMR2, BRK 3, FLJ41585, FLJ76945, PPH1, T ALK
Background

BMPs (bone morphogenetic protein) are involved in endochondral bone formation and embryogenesis. BMPR2 encodes a member of the (BMP) receptor family of transmembrane serine/threonine kinases. It is a widely expressed receptor, with high mRNA expression during development in many tissues. Dimer of BMPR2 receptors (70-80 kD) forms a complex with a dimer of type I BMPR1(50-55 kD) in signal transduction. This antibody recognizes endogenous levels of total BMPR2 protein, including 115 kD precursor, 75 kD mature form and 150 kD dimer.


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