Mouse CD28 Recombinant antibody, PBS Only (Detector)

CD28 Uni-rAbTM Recombinant Antibody for IF/ICC, Cytometric bead array, Indirect ELISA
Cat No. 84368-4-PBS
Clone No.241707H6

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

IF/ICC, Cytometric bead array, Indirect ELISA

T-cell-specific surface glycoprotein CD28, CD28 antigen, 241707H6

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

84368-4-PBS targets CD28 as part of a matched antibody pair:

MP01248-3: 84368-5-PBS capture and 84368-4-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Reactivity mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein Predict reactive species
Full Name CD28 antigen
Calculated Molecular Weight25 kDa
GenBank Accession NumberNM_007642.4
Gene Symbol Cd28
Gene ID (NCBI) 12487
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP31041
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

CD28 (T-cell-specific surface glycoprotein CD28), also known as T44 and Tp44, is a 44 kD disulfide-linked homodimeric type I glycoprotein (PMID: 2162180). It is a member of the immunoglobulin superfamily and is expressed on most T lineage cells, NK cell subsets, and plasma cells (PMID: 2162180, 8386518). CD28 may affect in vivo immune responses by functioning both as a cell adhesion molecule linking B and T lymphocytes and as the surface component of a novel signal transduction pathway (PMID: 2162180, 3021470). CD28 binds both CD80 and CD86 with a highly conserved motif MYPPY in the CDR3-like loop (PMID: 15696168, 7964482). CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death (PMID: 1348520).

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