|Positive IF detected in||THP-1 cells|
|Positive FC detected in||human PBMCs, THP-1 cells|
|Immunofluorescence (IF)||IF : 1:200-1:800|
|This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.|
|Sample-dependent, check data in validation data gallery|
65187-1-Ig targets CD68 in IF, FC applications and shows reactivity with Human samples.
|Host / Isotype||Mouse / Mouse IgG2a|
|Immunogen||Lysosomal contents of lung macrophages|
|Full Name||CD68 molecule|
|Calculated molecular weight||37 kDa|
|GenBank accession number||BC015557|
|Gene ID (NCBI)||968|
|Purification Method||Protein A purification|
|Storage Buffer||PBS with 0.1% sodium azide.|
|Storage Conditions||Store at 2-8°C.|
CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.