Anti-Human CD68 (Y1/82A)

CD68 Monoclonal Antibody for FC, IF

Host / Isotype

Mouse / Mouse IgG2a

Reactivity

Human and More (1)

Applications

IF, FC

Conjugate

Unconjugated

CloneNo.

Y1/82A

Cat no : 65187-1-Ig

Synonyms

CD68, CD68 molecule, DKFZp686M18236, GP110, Macrosialin, SCARD1



Tested Applications

Positive IF detected inTHP-1 cells
Positive FC detected inhuman PBMCs, THP-1 cells
Planning an IHC experiment? We recommend our IHCeasy CD68 Ready-To-Use IHC Kit. CD68 primary antibody included.

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:200-1:800
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Published Applications

FCSee 1 publications below

Product Information

65187-1-Ig targets CD68 in IF, FC applications and shows reactivity with Human samples.

Tested Reactivity Human
Cited Reactivitymouse
Host / Isotype Mouse / Mouse IgG2a
Class Monoclonal
Type Antibody
Immunogen Lysosomal contents of lung macrophages
Full Name CD68 molecule
Calculated molecular weight 37 kDa
GenBank accession numberBC015557
Gene symbol CD68
Gene ID (NCBI) 968
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.1% sodium azide.
Storage ConditionsStore at 2-8°C.

Background Information

CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.

Protocols

Product Specific Protocols
IF protocol for CD68 antibody 65187-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseFC

Int Immunopharmacol

Macrophages regulates the transition of pericyte to peritoneal fibrosis through the GSDMD/IL-1β axis

Authors - Qiuyuan Shao