Properdin/PFC Polyclonal antibody, PBS Only

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  WB analysis of Jurkat using 17192-1-AP (same clone as 17192-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 17192-1-AP (CFP Antibody) at dilution of 1:300 incubated at 4 degree celsius over night. This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

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  IHC staining of human spleen using 17192-1-AP (same clone as 17192-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 17192-1-AP (CFP Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human spleen using 17192-1-AP (same clone as 17192-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 17192-1-AP (CFP Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

Properdin/PFC Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 17192-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Synonyms

CFP, PFC, complement factor properdin, Complement factor P, BFD

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Product Information

17192-1-PBS targets Properdin/PFC in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Properdin/PFC fusion protein Ag9798
• Full Name: complement factor properdin
• Calculated Molecular Weight: 469 aa, 51 kDa
• Observed Molecular Weight: 50 kDa
• GenBank Accession Number: BC015756
• Gene Symbol: CFP
• Gene ID (NCBI): 5199
• RRID: AB_2878359
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P27918
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

CFP, also named as Properdin or CFP, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105).