- Featured Product
- KD/KO Validated
CoraLite® Plus 488-conjugated CNOT1 Monoclonal antibody
CNOT1 Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG1
CoraLite® Plus 488 Fluorescent Dye
Cat no : CL488-66507
|Positive IF detected in
|IF : 1:50-1:500
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
CL488-66507 targets CNOT1 in IF applications and shows reactivity with Human samples.
|Host / Isotype
|Mouse / IgG1
|CNOT1 fusion protein Ag5623
|CCR4-NOT transcription complex, subunit 1
|Calculated molecular weight
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|CoraLite® Plus 488 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|493 nm / 522 nm
|Protein G purification
|PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
|Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
CNOT1 is a component of CCR4-NOT protein complex, which is a regulator of RNA polymerase II transcription, acts as a transcription repressor. CCR4-NOT complex could participate in transcription as well as mRNA degradation. It's highly expressed in brain, heart, thymus, but weak in skeletal muscle and colon. CNOT1 undergoes alternative splicing to produce four isoforms. CNOT1 exsits as many isoforms. The isoform one is about 267 kDa and the isoform four is about 173 kDa.