CRX Monoclonal antibody
CRX Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat, pig
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
1C3C11
Cat no : 67555-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | rat retina tissue, Y79 cells, mouse retina tissue, pig retina tissue |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:1000-1:6000 |
Sample-dependent, check data in validation data gallery |
Product Information
67555-1-Ig targets CRX in WB, ELISA applications and shows reactivity with Human, mouse, rat, pig samples.
Tested Reactivity | Human, mouse, rat, pig |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | CRX fusion protein Ag30086 |
Full Name | cone-rod homeobox |
Calculated molecular weight | 299 aa, 32 kDa |
Observed molecular weight | 37 kDa |
GenBank accession number | BC016664 |
Gene symbol | CRX |
Gene ID (NCBI) | 1406 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Cone-rod homeobox (Crx) is a homeodomain transcription factor and member of the Otx family, which has been thought to play a critical role in determining and maintaining the phenotype of both pinealocytes and retinal photoreceptors [PMID:17467693]. In the mammalian retina, Crx plays an essential role in the normal development and maintenance of cones and rods and regulates expression of the network of genes that characterize the retina [PMID:17653270]. Elimination of Crx by disruption of the homeobox domain results in loss of the image-forming visual system but not the non-image-forming visual system controlling circadian rhythms [PMID:20438719].
Protocols
Product Specific Protocols | |
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WB protocol for CRX antibody 67555-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |