Recombinant Human EMB protein (rFc Tag)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg6407
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human EMB protein Asp33-Pro260 (Accession# Q6PCB8) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | 133418 |
| Accession | Q6PCB8 |
| PredictedSize | 51.4 kDa |
| SDS-PAGE | 60-90 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
The transmembrane glycoprotein embigin (EMB) belongs to the immunoglobulin superfamily (IgSF) and a number of IgSF members have been identified as biomarkers for cancer progression. EMB has been widely known as developmentally expressed protein that is involved in prostate and mammary gland development and in the early stages of mouse embryogenesis.
References:
1. Chao, Fengmei et al. Oncotarget vol. 6,27 (2015): 23496-509. 2. Ruma, I Made Winarsa et al.Cancers (Basel). vol. 10,7 (2018) 239. 3. Xu, Binghong et al. Cell Rep. vol. 40,11 (2022): 111343.