Insulin Antibody 11 Publications

Rabbit Polyclonal| Catalog number: 15848-1-AP

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Freight/Packing

Con: 42 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
BxPC-3 cells, mouse pancreas tissue

Positive IHC detected in:
human pancreas tissue, human pancreas tissue, mouse pancreas tissue, rat pancreas tissue

Positive IF detected in:
rat pancreas

Recommended dilution:
WB : 1:500-1:3000
IHC : 1:500-1:1000
IF : 1:100-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
insulin

Calculated molecular weight:
110aa,12 kDa

Observed molecular weight:
30 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
INS

Synonyms
ILPR, INS, insulin, IRDN
Background

Insulin is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form.


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