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IQGAP2 Polyclonal antibody, PBS Only

IQGAP2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 30692-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

IQGAP 2

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

30692-1-PBS targets IQGAP2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag33518

Product name: Recombinant human IQGAP2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 519-727 aa of NM_006633

Sequence: DEIQQAVDDANVDKDRAKQWVTLVVDVNQCLEGKKSSDILSVLKSSTSNANDIIPECADKYYDALVKAKELKSERVSSDGSWLKLNLHKKYDYYYNTDSKESSWVTPESCLYKESWLTGKEIEDIIEEVTVGYIRENIWSASEELLLRFQATSSGPILREEFEARKSFLHEQEENVVKIQAFWKGYKQRKEYMHRRQTFIDNTDSIVKI

Predict reactive species
Full Name IQ motif containing GTPase activating protein 2
Calculated Molecular Weight181 kDa
Observed Molecular Weight181 kDa
GenBank Accession NumberNM_006633
Gene Symbol IQGAP2
Gene ID (NCBI) 10788
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ13576
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

IQGAP2, a member of the IQGAP family, functions as a tumor suppressor in most of the cancers. IQGAP2 contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. IQGAP2 interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses.

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