Cytokeratin 17 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22230-1-AP

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Con: 53 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
HeLa cells, MCF-7 cells

Positive IHC detected in:
human cervical cancer tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
keratin 17

Calculated molecular weight:
432aa,48 kDa

Observed molecular weight:
48 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KRT17

Synonyms
39.1, CK 17, Cytokeratin 17, K17, keratin 17, KRT17, PC, PC2, PCHC1
Background

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin 17 is a type I cytokeratin. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. It is used as a marker for trauma.


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