CoraLite® Plus 488-conjugated LAIR1 Monoclonal antibody

LAIR1 Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG2a






CoraLite® Plus 488 Fluorescent Dye



Cat no : CL488-67220


CD305, hLAIR1, LAIR 1, LAIR1

Tested Applications

Positive IF detected inhuman tonsillitis tissue

Recommended dilution

Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

CL488-67220 targets LAIR1 in IF applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen LAIR1 fusion protein Ag14459
Full Name leukocyte-associated immunoglobulin-like receptor 1
Calculated molecular weight 287 aa, 31 kDa
GenBank accession numberBC027899
Gene symbol LAIR1
Gene ID (NCBI) 3903
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) is a transmembrane glycoprotein with a single immunoglobulin-like domain and a cytoplasmic tail containing two immune receptor tyrosine-based inhibitory motifs (PMID: 9285412). LAIR1 is expressed on the majority of human PBMCs, including NK, T, B, monocytes, and dendritic cells, as well as the majority of thymocytes (PMID: 10229813). It functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of NK cells, B cells and T cells. LAIR1 is a collagen receptor (PMID: 16754721). Tumor-expressed collagens can modulate immune cell function through the inhibitory collagen receptor LAIR1 (PMID: 21955987).


Product Specific Protocols
IF protocol for CL Plus 488 LAIR1 antibody CL488-67220Download protocol
Standard Protocols
Click here to view our Standard Protocols