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Lin28B-specific Polyclonal antibody

Lin28B-specific Polyclonal Antibody for IF, IHC, ELISA

Host / Isotype

Rabbit / IgG


human and More (2)





Cat no : 16178-1-AP


CSDD2, lin 28 homolog B (C. elegans), Lin 28B, Lin28, LIN28B, Lin28B-specific, Protein lin 28 homolog B

Tested Applications

Positive IHC detected inhuman colon cancer tissue, human testis tissue, human brain tissue, human spleen tissue, human liver cancer tissue, human lung tissue, human kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHepG2 cells

Recommended dilution

Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:10-1:100
Sample-dependent, check data in validation data gallery

Product Information

16178-1-AP targets Lin28B-specific in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name lin-28 homolog B (C. elegans)
Calculated molecular weight 28 kDa
Observed molecular weight27 kDa
GenBank accession numberNM_001004317
Gene symbol LIN28B
Gene ID (NCBI) 389421
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

LIN28B, also named as CSDD2, belongs to the lin-28 family. It acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7). LIN2B is specifically expressed in embryonic muscle, neurons, and epithelia, as well as in embryonic carcinoma cells. However, it is suppressed in most adult tissues except for skeletal and cardiac muscle. LIN2B shares 78% sequence identity with LIN28A. This antibody is specific to LIN28B.


Product Specific Protocols
IHC protocol for Lin28B-specific antibody 16178-1-APDownload protocol
IF protocol for Lin28B-specific antibody 16178-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Cell Rep

LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability.

Authors - Tugba Keskin

Cell Rep

LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma.

Authors - Tugba Keskin

Arch Oral Biol

Different expression patterns of Lin28 and Lin28b in mouse molar development.

Authors - Ning Dong

Tumour Biol

Expression and associations of TRAF1, BMI-1, ALDH1, and Lin28B in oral squamous cell carcinoma.

Authors - Tian-Fu Wu

Tumour Biol

JMJD1A promotes tumorigenesis and forms a feedback loop with EZH2/let-7c in NSCLC cells.

Authors - Min Zhan

PLoS One

Unique Haploinsufficient Role of the MicroRNA-Processing Molecule Dicer1 in a Murine Colitis-Associated Tumorigenesis Model.

Authors - Yoshikawa Takeshi T