NMDAR1/GRIN1 Recombinant antibody, PBS Only

NMDAR1/GRIN1 Uni-rAbTM Recombinant Antibody for WB, IP, Indirect ELISA
Cat No. 85973-3-PBS
Clone No.250535B1

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, Indirect ELISA

GRIN1, NMDAR1, GluN1, Glutamate receptor ionotropic, NMDA 1, NMDAR 1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

85973-3-PBS targets NMDAR1/GRIN1 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen NMDAR1/GRIN1 fusion protein Ag26093 Predict reactive species
Full Name glutamate receptor, ionotropic, N-methyl D-aspartate 1
Calculated Molecular Weight 105 kDa
Observed Molecular Weight116-120 kDa
GenBank Accession NumberNM_000832
Gene Symbol NMDAR1
Gene ID (NCBI) 2902
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ05586
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

GRIN1 encodes subunit 1 of the N-methyl-D-aspartate (NMDA) receptor, which is a heteromeric glutamate-gated calcium ion channel essential for synaptic function in the brain (PMID: 25864721, PMID: 25864721). NMDARs play important roles in normal brain development and function, such as synaptic plasticity, neural development, learning and memory (PMID: 20716669). NMDAR dysfunction has been associated with several neurological disorders including Parkinson, Alzheimer and Huntington diseases. Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum (PMID: 17015831).

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