NRF1/nuclear respiratory factor 1 Monoclonal antibody
NRF1/nuclear respiratory factor 1 Monoclonal Antibody for IF, WB, ELISA
Cat no : 66832-1-Ig
|Positive WB detected in||HeLa cells|
|Positive IF detected in||HepG2 cells|
|Western Blot (WB)||WB : 1:5000-1:50000|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
66832-1-Ig targets NRF1/nuclear respiratory factor 1 in WB, IF, ELISA applications and shows reactivity with Human, mouse, rat samples.
|Tested Reactivity||Human, mouse, rat|
|Cited Reactivity||mouse, rat|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||NRF1/nuclear respiratory factor 1 fusion protein Ag28149|
|Full Name||nuclear respiratory factor 1|
|Calculated molecular weight||522 aa, 56 kDa|
|Observed molecular weight||70 kDa|
|GenBank accession number||BC016925|
|Gene ID (NCBI)||4899|
|Purification Method||Protein A purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
NRF1, also named as Alpha-pal and NRF-1, belongs to the NRF1/Ewg family. It is a transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. NRF1 is implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. It plays a critical role in regulating the expression of many antioxidant response element (ARE)-dependent genes. NRF1 exists various isoforms and long isoform is about 67 kDa and short isoform is about 45 kDa.
J Clin Transl Hepatol
Icaritin Attenuates Lipid Accumulation by Increasing Energy Expenditure and Autophagy Regulated by Phosphorylating AMPK.
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.