TrkA Monoclonal antibody, PBS Only

• 

  WB analysis using 60548-1-Ig (same clone as 60548-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

• 

  WB analysis of NK-92 using 60548-1-Ig (same clone as 60548-1-PBS)

  NK-92 cells were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 60548-1-Ig (same clone as 60548-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

TrkA Monoclonal Antibody for WB, Indirect ELISA

Cat No. 60548-1-PBS

Clone No.3B11C7

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

NTRK1, Trk A, TRK, p140 TrkA, MTC

---

Product Information

60548-1-PBS targets TrkA in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag27985

  Product name: Recombinant human NTRK1 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 80-277 aa of NM_001007792

  Sequence: MQHLELRDLRGLGELRNLTIVKSGLRFVAPDAFHFTPRLSRLNLSFNALESLSWKTVQGLSLQELVLSGNPLHCSCALRWLQRWEEEGLGGVPEQKLQCHGQGPLAHMPNASCGVPTLKVQVPNASVDVGDDVLLRCQVEGRGLEQAGWILTELEQSATVMKSGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVS

• Full Name: neurotrophic tyrosine kinase, receptor, type 1
• Calculated Molecular Weight: 88 kDa
• Observed Molecular Weight: 140 kDa
• GenBank Accession Number: NM_001007792
• Gene Symbol: NTRK1
• Gene ID (NCBI): 4914
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• UNIPROT ID: P04629
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

NTRK1(Neurotrophic tyrosine kinase receptor 1) is located on chromosome 1q23.1 and is responsible for a rare genetic disorder, CIPA (congenital insensitivity to pain with anhidrosis) (PMID: 37907480). As a neurotrophin receptor, NTRK1 is abundantly expressed in human neuronal tissues and plays an integral role in the development and function of the human nervous system (PMID: 27843590). NTRK1 also regulates the survival and proliferation of cholinergic neurons (PMID: 20054812).