Product Information
18156-1-PBS targets Piccolo in IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Piccolo fusion protein Ag12952 Predict reactive species |
Full Name | piccolo (presynaptic cytomatrix protein) |
Calculated Molecular Weight | 553 kDa |
GenBank Accession Number | BC001304 |
Gene Symbol | Piccolo |
Gene ID (NCBI) | 27445 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9Y6V0 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
Piccolo is a presynaptic scaffolding protein of the cytomatrix assembled at the active zone (AZ). AZ is a special region of the presynaptic plasma membrane where synaptic vesicles (SVs) fuse. It has been shown that Piccolo affects presynaptic function by negatively regulating SV exocytosis (PMID: 18519737).