Neuroserpin Polyclonal antibody
Neuroserpin Polyclonal Antibody for WB,ELISA
Host / Isotype
Rabbit / IgG
human, mouse, rat
Cat no : 12558-1-AP
|Positive WB detected in
|mouse brain tissue
|Western Blot (WB)
|WB : 1:500-1:1000
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
12558-1-AP targets Neuroserpin in WB,ELISA applications and shows reactivity with human, mouse, rat samples.
|human, mouse, rat
|Host / Isotype
|Rabbit / IgG
|Neuroserpin fusion protein Ag3275
|serpin peptidase inhibitor, clade I (neuroserpin), member 1
|Calculated molecular weight
|410 aa, 47 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Antigen affinity purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
Neuroserpin is a member of the serpin family of serine protease inhibitors predominantly expressed in the nervous system, such as s the cerebral cortex, hippocampus and the spinal cord.Neuroserpin exerts protective effects in neurons against excitotoxicity both in vitro and in vivo. Its proteolytic inhibitory activity is shown to protect neurons against damage caused by plasmin activation. Mice overexpressing neuroserpin exhibited loss of tPA activity in the brain. Overexpression of neuroserpin in primary neurons leads to increased dendritic arborization and altered dendritic spine shape.