|Positive WB detected in||pig brain tissue, HEK-293 cells|
|Western Blot (WB)||WB : 1:5000-1:20000|
|Sample-dependent, check data in validation data gallery|
66488-1-Ig targets VAMP3/Cellubrevin in WB,ELISA applications and shows reactivity with Human, Mouse, Rat, Pig samples.
|Tested Reactivity||Human, Mouse, Rat, Pig|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||VAMP3/Cellubrevin fusion protein Ag1156|
|Full Name||vesicle-associated membrane protein 3 (cellubrevin)|
|Calculated molecular weight||11 kDa|
|Observed molecular weight||17 kDa|
|GenBank accession number||BC005941|
|Gene ID (NCBI)||9341|
|Purification Method||Protein A purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
VAMP3, also named as cellubrevin or synaptobrevin 3, is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. VAMP3 is a v-SNARE (soluble NSF-attachment protein receptor). Characterized by a common sequence called the SNARE motif, SNARE proteins are involved in membrane fusion and vesicular transport (PMID: 11252968). VAMP3 resides in recycling endosomes and endosome-derived transport vesicles, involved in regulating membrane traffic. It is implicated in recycling of transferrin receptors, secretion of alpha-granules in platelets, and membrane trafficking during cell migration.