cIAP1 Monoclonal antibody

cIAP1 Monoclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Mouse / IgG1


Human, mouse, rat, pig and More (1)







Cat no : 66626-1-Ig


API1, BIRC2, C IAP1, cIAP1, Hiap 2, HIAP2, IAP 2, IAP homolog B, IAP2, MIHB, RING finger protein 48, RNF48

Tested Applications

Positive WB detected inA431 cells, HEK-293 cells, HepG2 cells, Hela cells, Jurkat cells, HSCT6 cells, pig brain tissue, rat brain tissue
Positive IHC detected inhuman spleen tissue, human tonsillitis tissue, human lung cancer tissue, human lymphoma tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHepG2 cells

Recommended dilution

Western Blot (WB)WB : 1:2000-1:10000
Immunohistochemistry (IHC)IHC : 1:150-1:600
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

66626-1-Ig targets cIAP1 in WB, IP, IHC, IF, ELISA applications and shows reactivity with Human, mouse, rat, pig samples.

Tested Reactivity Human, mouse, rat, pig
Cited Reactivityhuman, mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen cIAP1 fusion protein Ag21398
Full Name baculoviral IAP repeat-containing 2
Calculated Molecular Weight 618 aa, 70 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC016174
Gene Symbol BIRC2
Gene ID (NCBI) 329
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

BIRC2 (also known as cIAP1) is a member of the inhibitor of apoptosis protein (IAP) family. The inhibitor of apoptosis (IAP) proteins are a family of anti-apoptotic regulators found in viruses and metazoans. BIRC2 is a nuclear shuttling protein, whose subcellular localization is mediated by the CRM1-dependent nuclear export pathway (PMID: 15265700). The protein is regulated transcriptionally and can be inhibited by mitochondrial proteins released in the cytoplasm upon apoptotic stimuli (PMID: 15187025). BIRC2 is also believed to be a critical regulator of vascular integrity and endothelial cell survival, thereby providing an additional target pathway for the control of angiogenesis and blood vessel homeostasis during embryogenesis, regeneration and tumorigenesis (PMID: 17934460).


Product Specific Protocols
WB protocol for cIAP1 antibody 66626-1-IgDownload protocol
IHC protocol for cIAP1 antibody 66626-1-IgDownload protocol
IF protocol for cIAP1 antibody 66626-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Cell Death Dis

Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells.

Authors - Jingru Huangfu

Chem Biol Interact

Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65

Authors - Jingwen Tan

J Exp Clin Cancer Res

TRIM56 promotes malignant progression of glioblastoma by stabilizing cIAP1 protein

Authors - Xu Yang

JACC Basic Transl Sci

Bag3 Regulates Mitochondrial Function and the Inflammasome Through Canonical and Noncanonical Pathways in the Heart

Authors - JuFang Wang


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Shubham (Verified Customer) (10-04-2019)


  • Applications: Immunoprecipitation,
  • Cell Tissue Type: AC16
cIAP1 Antibody Immunoprecipitation, validation ( dilution) in AC16 (Cat no:66626-1-Ig)