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C-FOS – a meaningful marker
Nuclear phosphoprotein c-FOS is also known as Proto-oncogene c-Fos and G0/G1 switch regulatory protein 7. One of the main functions of c-FOS is regulation of the development of cells destined to form and maintain the skeleton.
c-fos as a transcription factor acts in conjunction with other proteins to induce transcription of a wide variety of genes.
c-fos expression is used as a marker of functional activity in the brain.
c-fos expression is associated with tumour progression.
Antibody |
Type |
Catalog number |
Applications |
C-FOS Antibody | Rabbit Polyclonal |
26192-1-AP |
ELISA, WB |
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Mouse embryo tissue was subjected to SDS PAGE followed by western blot with 26192-1-AP(FOS Antibody) at a dilution of 1:1000. |
Prestained Protein Marker (free samples available) | Broad Range Prestained Protein Marker |
10 prestained proteins covering a wide range of molecular weights from 10 to 180 kDa | 13 prestained proteins covering a wide range of molecular weights from 3 to 245 kDa |
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Resolution of the prestained protein ladder in a 10-20% Tris-glycine gel (SDS-PAGE). | Resolution of the prestained protein ladder in a 4-12% Bis-Tris gel (SDS-PAGE). |
1. The c-FOS Protein Immunohistological Detection: A Useful Tool As a Marker of Central Pathways Involved in Specific Physiological Responses In Vivo and Ex Vivo. https://www.ncbi.nlm.nih.gov/pubmed/27167092
2. IL-17 mediates inflammatory reactions via p38/c-Fos and JNK/c-Jun activation in an AP-1-dependent manner in human nucleus pulposus cells. https://www.ncbi.nlm.nih.gov/pubmed/26988982
3. New technologies for examining neuronal ensembles in drug addiction and fear https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530016/
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