FLNC Polyclonal antibody

FLNC Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB,ELISA

Conjugate

Unconjugated

Cat no : 28492-1-AP

Synonyms

ABP 280, ABP 280 like protein, ABP L, ABP280A, ABPA, ABPL, Actin binding like protein, Filamin 2, Filamin C, FLJ10186, FLN C, FLN2, FLNC, Gamma filamin



Tested Applications

Positive WB detected inSGC-7901 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Sample-dependent, check data in validation data gallery

Product Information

28492-1-AP targets FLNC in WB,ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FLNC fusion protein Ag29328
Full Name filamin C, gamma (actin binding protein 280)
Calculated molecular weight 291 kDa
Observed molecular weight 280-300 kDa
GenBank accession numberNM_001458
Gene symbol FLNC
Gene ID (NCBI) 2318
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Filamin C (FLNC; also known as γ-FLN; ABP-L; FLN2), a muscle-specific filamin and a large actin-cross-linking protein. Human filamins are ~280 kDa homodimers, each monomer consisting of an N-terminal actin-binding domain followed by 24 immunoglobulin (Ig)-like domains (d1 to d24), the last of which mediates dimerization. FLNC is specifically expressed in cardiomyocytes and skeletal myocytes and is involved in the maintenance of structural integrity. High filamin C associated with better prognosis of prostate cancer, leukemia and breast cancer patients. ( PMID: 25577646, PMID: 30867563, PMID: 31131323)

Protocols

Product Specific Protocols
WB protocol for FLNC antibody 28492-1-APDownload protocol
Standard Protocols
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