FLNC Polyclonal antibody

FLNC Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG


Human and More (1)





Cat no : 28492-1-AP


ABP 280, ABP 280 like protein, ABP L, ABP280A, ABPA, ABPL, Actin binding like protein, Filamin 2, Filamin C, FLJ10186, FLN C, FLN2, FLNC, Gamma filamin

Tested Applications

Positive WB detected inSGC-7901 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 1 publications below

Product Information

28492-1-AP targets FLNC in WB, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FLNC fusion protein Ag29328
Full Name filamin C, gamma (actin binding protein 280)
Calculated Molecular Weight 291 kDa
Observed Molecular Weight 280-300 kDa
GenBank Accession NumberNM_001458
Gene Symbol FLNC
Gene ID (NCBI) 2318
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Filamin C (FLNC; also known as γ-FLN; ABP-L; FLN2), a muscle-specific filamin and a large actin-cross-linking protein. Human filamins are ~280 kDa homodimers, each monomer consisting of an N-terminal actin-binding domain followed by 24 immunoglobulin (Ig)-like domains (d1 to d24), the last of which mediates dimerization. FLNC is specifically expressed in cardiomyocytes and skeletal myocytes and is involved in the maintenance of structural integrity. High filamin C associated with better prognosis of prostate cancer, leukemia and breast cancer patients. ( PMID: 25577646, PMID: 30867563, PMID: 31131323)


Product Specific Protocols
WB protocol for FLNC antibody 28492-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Int J Mol Sci

A Regulator Role for the ATP-Binding Cassette Subfamily C Member 6 Transporter in HepG2 Cells: Effect on the Dynamics of Cell-Cell and Cell-Matrix Interactions

Authors - Ilenia Matera