• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human TGF beta 3 protein- GMP grade

EC50

0.15-0.75 ng/mL EC50

Species Reactivity

Human

Purity

> 95%

ISO 13485 certified HumanKine® human cell-expressed cytokines and growth factors

Cat no : HZ-1090-GMP

Synonyms

ARVD, FLJ16571, TGF beta 3, TGF beta3, TGFB3



Technical Specifications

GeneID 7043
Species Human
Expression HEK293
EC50 0.15-0.75 ng/mL EC50
Purity > 95%
Endotoxin< 0.1 EU/µg
Accession NumberP10600
Molecular Mass 25 kDa, homodimer, non-glycosylated
Formulation 50 mM NaOAc pH 3.7, See Certificate of Analysis for details
Species Reactivity human,mouse

Stability and Reconstitution

Stability and Storage Lyophilized proteins are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin (HSA).

GMP Quality Policies

HumanKine® GMP (Good Manufacturing Practice) recombinant proteins are manufactured and validated in accordance with ISO 13485 quality management system and is compliant with GMP.
Our GMP recombinant proteins are animal component free (ACF), xeno free (XF) and tag free (TF). Read more about these policies here.

Background

The transforming growth factor beta-3 (TGFβ-3) protein is found throughout the body and is required for development before birth and throughout life. TGFβ-3 binds to the receptor proteins on the surface of cells. This binding triggers the transmission of signals within the cell. As part of the TGF-β a signalling pathway, the TGFβ-3 protein helps to control the growth and cell proliferation. The TGFβ-3 protein is especially abundant in skeletal muscles and plays a key role in their development. The protein is also involved in blood vessels formation, regulation of bone growth, and wound healing (PMID: 25835445; 23824657)

Synonyms

ARVD, FLJ16571, TGF beta 3, TGF beta3, TGFB3