CBP,EIF4E Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 11149-1-AP

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Con: 26 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HEK-293 cells

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human gliomas tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
eukaryotic translation initiation factor 4E

Calculated molecular weight:
29 kDa

Observed molecular weight:
26-29 kDa, 50 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EIF4E

Synonyms
CBP, eIF 4E, eIF 4F 25 kDa subunit, EIF4E, EIF4E1, EIF4EL1, EIF4F, mRNA cap binding protein
Background

Eukaryotic translation initiation factor 4E(EIF4E) is the rate-limiting part of mRNA 7-methyl guanosine cap-binding component of the translation initiation complex eIF4F. The other subunits of EIF4F are a 50-kD polopeptied, terned EIF4A and a 220-kD polypeptied EIF4G. EIF4E mediates the binding to the mRNA cap then repress the translation. Due to the increasing expression of c-Myc in the oncogene, EIF4E's activity is enhance. This is a rabbit polyclonal antibody raised against the full-length of human EIF4E. This protein can form a dimer (~50 kDa).


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