Alpha galactosidase A Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66121-1-Ig |CloneNo.: 2B2C5

Featured Product KD/KO validated

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Freight/Packing

Con: 358 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HeLa cells,human kidney tissue, HepG2 cells, HEK-293 cells

Positive IHC detected in:
human kidney tissue, human kidney tissue, human liver tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
galactosidase, alpha

Calculated molecular weight:
49 kDa

Observed molecular weight:
49 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GLA

Synonyms
Alpha galactosidase A, galactosidase, alpha
Background

GLA, also named as Melibiase, Agalsidase and Alpha-galactosidase A, belongs to the glycosyl hydrolase 27 family. It hydrolyzes terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids. Fabry disease is an X-linked lysosomal storage disorder resulting from the deficient activity of GLA. Enzyme replacement therapy (ERT) with GLA is currently the most effective therapeutic strategy for patients with Fabry disease, a lysosomal storage disease.


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