CoraLite® Plus 488-conjugated AMH Polyclonal antibody

AMH Polyclonal Antibody for IF

Host / Isotype

Rabbit / IgG

Reactivity

human, rat, mouse

Applications

IF

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-23479

Synonyms

AMH, anti Mullerian hormone, MIF, MIS

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Validation Data Gallery

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  IF Staining of mouse ovary using CL488-23479

  Immunofluorescent analysis of (4% PFA) fixed mouse ovary tissue using CoraLite® Plus 488 AMH antibody (CL488-23479) at dilution of 1:200.

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  IF Staining of mouse ovary using CL488-23479

  Immunofluorescent analysis of (4% PFA) fixed mouse ovary tissue using CoraLite® Plus 488 AMH antibody (CL488-23479) at dilution of 1:200.

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Tested Applications

• Positive IF detected in: mouse ovary tissue

Recommended dilution

• Immunofluorescence (IF): IF : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

CL488-23479 targets AMH in IF applications and shows reactivity with human, rat, mouse samples.

• Tested Reactivity: human, rat, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: AMH fusion protein Ag20166
• Full Name: anti-Mullerian hormone
• Calculated Molecular Weight: 59 kDa
• GenBank Accession Number: BC049194
• Gene Symbol: AMH
• Gene ID (NCBI): 268
• Conjugate: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 493 nm / 522 nm
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
• Storage Conditions: Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Anti-Müllerian hormone (AMH), also called Müllerian-inhibiting substance (MIS), is a dimeric glycoprotein and a member of the TGF-β family. AMH, produced by the Sertoli cells of the fetal testis, induces the regression of the Müllerian ducts, the anlagen of the female reproductive tract. However, after birth, this sex-dimorphic expression pattern is lost and AMH is also expressed in granulosa cells of growing follicles in the ovary. More recently, AMH has been studied for its role in ovarian folliculogenesis and as a potential marker of ovarian reserve.