CoraLite®594-conjugated APOE Monoclonal antibody
APOE Monoclonal Antibody for FC (Intra)
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse
Applications
FC (Intra)
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
1B2C9
Cat no : CL594-66830
Synonyms
Validation Data Gallery
Tested Applications
Positive FC detected in | HepG2 cells |
Recommended dilution
Application | Dilution |
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Sample-dependent, check data in validation data gallery |
Product Information
CL594-66830 targets APOE in FC (Intra) applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | APOE fusion protein Ag28186 |
Full Name | apolipoprotein E |
Calculated molecular weight | 36 kDa |
Observed molecular weight | 34-36 kDa |
GenBank accession number | BC003557 |
Gene symbol | APOE |
Gene ID (NCBI) | 348 |
Conjugate | CoraLite®594 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
The apolipoprotein E (APOE) is a 299-amino acid polypeptide that mediates the binding, internalization, and catabolism of lipoprotein particles, and also serve as a ligand for the LDL (APO B/E) receptor and for the specific APOE receptor (chylomicron remnant) of hepatic tissues. The very strong association of the APOE ɛ4 allele with AD risk and its role in the accumulation of amyloid β in brains of people and animal models solidify the biological relevance of APOE isoforms but do not provide mechanistic insight.
Protocols
Product Specific Protocols | |
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FC protocol for CL594 APOE antibody CL594-66830 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |