BRD8 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10476-1-AP

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Freight/Packing

Con: 48 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HeLa cells, human brain tissue

Positive IP detected in:
HeLa cells

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
bromodomain containing 8

Calculated molecular weight:
120 kDa

Observed molecular weight:
120 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BRD8

Synonyms
BRD8, bromodomain containing 8, p120, SMAP, SMAP2, TrCP120
Background

BRD8 is one of the bromodomain-containing proteins, which is an acetylated lysine- binding domain and thought to be involved in regulation of protein acetylation and/or HAT (histone acetyl transferase) activity [PMID: 12963728]. It is also reported to be an accessory subunit of NuA4 HAT complex (also known as TRRAP/TIP60 complex) through biochemical purification [PMID: 16049979]. In addition, it can bind to thyroid hormone receptor-ß and/or retinoid X receptor, and can act as a coactivator of the nuclear hormone receptor-mediated transcription in reporter assays [PMID: 10517671].


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