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CD38 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 25284-1-AP

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Con: 49 μg/150 μl

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Tested Applications

Applications:
WB, IHC, IF, FC, ELISA
Application not tested? Please see our Guarantee


Images See all

CD38 Antibody IHC human tonsillitis tissue 25284-1-AP

Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 25284-1-AP( CD38 Antibody) at dilution of 1:50 (under 10x lens)

CD38 Antibody IHC human tonsillitis tissue 25284-1-AP

Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 25284-1-AP( CD38 Antibody) at dilution of 1:50 (under 40x lens)

CD38 Antibody WB HL-60 cells 25284-1-AP

HL-60 cells were subjected to SDS PAGE followed by western blot with 25284-1-AP( CD38 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours

CD38 Antibody FC HL-60 cells 25284-1-AP

1X10^6 HL-60 cells were stained with 0.2ug CD38 antibody (25284-1-AP, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.

Species specificity:
human
Positive WB detected in:
HL-60 cells, Raji cells
Positive IHC detected in:
human tonsillitis tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive FC detected in:
HL-60 cells
Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
Sample-dependent, check data in Validation tab

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
CD38 fusion protein Ag17868
Full name:
CD38 molecule
Calculated molecular weight:
300aa,34 kDa
Observed molecular weight:
42 kDa
GenBank accession number:
BC007964
Gene ID (NCBI):
952
Gene symbol
CD38
Synonyms
ADP ribosyl cyclase 1, cADPr hydrolase 1, CD38, CD38 molecule, Cyclic ADP ribose hydrolase 1, T10

Background

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).


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