GPT2 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 16757-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse kidney tissue, human skeletal muscle tissue

Positive IP detected in:
mouse kidney tissue

Positive IHC detected in:
human skeletal muscle tissue, mouse brain tissue, human kidney tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
glutamic pyruvate transaminase (alanine aminotransferase) 2

Calculated molecular weight:
523aa,58 kDa

Observed molecular weight:
58 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GPT2

Synonyms
AAT2, Alanine aminotransferase 2, ALT2, GPT 2, GPT2
Background

GPT2 (Alanine aminotransferase 2; ALT2) is a key enzyme in intermediatary metabolism, catalysing the reversible transfer of the amino group of glutamate to pyruvate, yielding alanine and ketoglutarate. GPT2 protein localizes to mitochondria, and is mainly expressed in the pancreas, brain, adrenal gland, skeletal muscle and heart. Serum GPT2 is a useful marker for liver damage. Recently mutation of GPT2 has been reported to be a cause of neural disorder (27601654).


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