Cytokeratin 14 Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 10143-1-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 54 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
A431 cells, rat skin tissue

Positive IP detected in:
A431 cells

Positive IHC detected in:
human lung cancer tissue, human cervical cancer tissue, human kidney tissue, human liver tissue, human lung cancer tissue, human oesophagus cancer tissue, human placenta tissue, human prostate hyperplasia tissue, human skin tissue, human skin cancer tissue, mouse skin tissue

Positive IF detected in:
HeLa cells, mouse olfactory epithelium tissue

Positive FC detected in:
A431 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
keratin 14

Calculated molecular weight:
472aa,52 kDa

Observed molecular weight:
47-50 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KRT14

Synonyms
CK 14, CK14, Cytokeratin 14, EBS3, EBS4, K14, keratin 14, KRT14, NFJ
Background

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin 14 is a type I cytokeratin. It is usually found as a heterotetramer with keratin 5. Keratins K14 and K5 have long been considered to be biochemical markers of the stratified squamous epithelia, including epidermis.


Back
to top