MAGOH Monoclonal antibody
MAGOH Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG1
Human, MOUSE, RAT, RABBIT
Cat no : 68293-1-Ig
|Positive WB detected in
|LNCaP cells, HeLa cells, HEK-293 cells, Jurkat cells, K-562 cells
|Western Blot (WB)
|WB : 1:5000-1:50000
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
68293-1-Ig targets MAGOH in WB, ELISA applications and shows reactivity with Human, MOUSE, RAT, RABBIT samples.
|Human, MOUSE, RAT, RABBIT
|Host / Isotype
|Mouse / IgG1
|MAGOH fusion protein Ag3004
|mago-nashi homolog, proliferation-associated (Drosophila)
|Calculated molecular weight
|146 aa, 17 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Protein G purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
MAGOH, belonging to the mago nashi family, is a component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC functions to mark the position of the exon-exon junction in the mature mRNA and thereby influences downstream processes of gene expression including mRNA splicing, nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). MAGOH regulates the transcriptional activation of STAT3 by interfering complex formation between STAT3 and a core EJC component Y14.