• Featured Product
  • KD/KO Validated

SOX5 Polyclonal antibody

SOX5 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (1)

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 13216-1-AP

Synonyms

L SOX5, SOX5, Transcription factor SOX 5



Tested Applications

Positive WB detected inA549 cells, SH-SY5Y cells, U-87 MG cells, mouse liver tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:10000
Sample-dependent, check data in validation data gallery

Product Information

13216-1-AP targets SOX5 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SOX5 fusion protein Ag4092
Full Name SRY (sex determining region Y)-box 5
Calculated molecular weight 763 aa, 84 kDa
Observed molecular weight 68-70 kDa
GenBank accession numberBC029220
Gene symbol SOX5
Gene ID (NCBI) 6660
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Sex determining region Y-box protein 5 (SOX5) is a member of the SOX family, which was identified based on the conserved homology of the high-mobility group DNA-binding motif. It has been reported that SOX5 is involved in the regulation of embryonic development, and is associated with various cancer types, including prostate cancer, glioblastoma, hepatocellular carcinoma, osteosarcoma and nasopharyngeal carcinoma. SOX5 has 5 isoforms with the molecular mass of 42, 71 and 82-84 kDa. (PMID: 30854049)

Protocols

Product Specific Protocols
WB protocol for SOX5 antibody 13216-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Nat Commun

VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.

Authors - Yuki Miyamoto
mouse,ratWB

Pharmacol Res

Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways.

Authors - Jiale Cai
humanWB,IHC

Cell Oncol (Dordr)

Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells.

Authors - Lihua Chen
  • KD Validated
humanWB

Phytomedicine

Transcriptomics, molecular docking, and cross-resistance profiling of nobiletin in cancer cells and synergistic interaction with doxorubicin upon SOX5 transfection.

Authors - Aveen N Adham
  • KO Validated
humanWB

Lab Invest

Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.

Authors - Min Feng
mouseIF

Mol Cell Biochem

Expression profiles of Sox transcription factors within the postnatal rodent testes.

Authors - Pauline Roumaud