- HEK293 expressed
- Endotoxin-free
- Animal-component free
HumanKine® recombinant human IL-7 protein
Activity
0.2-1.4 ng/mL EC50
Specific Activity
2.53E8 IU/mg calibrated against Human IL-7 reference standard (NIBSC cat no: 90/530). Reference use only. Specific activity is not routinely tested
Species Reactivity
human,mouse
Purity
>95%
Cat no : HZ-1281
Synonyms
IL 7, IL7, IL-7, interleukin 7
Validation Data Gallery
Technical Specifications
GeneID | 3574 |
Species | Human |
Expression | HEK293 |
Activity | 0.2-1.4 ng/mL EC50 |
Specific Activity | 2.53E8 IU/mg calibrated against Human IL-7 reference standard (NIBSC cat no: 90/530). Reference use only. Specific activity is not routinely tested |
Purity | >95% |
Endotoxin | <1 EU/μg |
Accession Number | P10168 |
Molecular Mass | 19, 25, and 30 kDa, monomer, glycosylated |
Formulation | 1x PBS, See Certificate of Analysis for details |
Species Reactivity | human,mouse |
Stability and Reconstitution
Stability and Storage | Product Form | Temperature Conditions | Storage Time (From Date of Receipt) |
---|---|---|---|
Lyophilized | -20°C to -80°C | Until Expiry Date | |
Lyophilized | Room Temperature | 2 weeks | |
Reconstituted as per CofA | -20°C to -80°C | 6 months | |
Reconstituted as per CofA | 4°C | 1 week | |
Avoid repeated freeze-thaw cycles. |
Reconstitution | Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA). |
Background
Interleukin-7 (IL7) is a cytokine involved in B and T cell development. It plays an active role in the development, survival, maintaining and restoring homeostasis of mature T lymphocytes and is a key regulator of the commitment, survival, proliferation and maturation of B cells during development. Furthermore, IL7 can improve the antiviral function and expansion of natural killer (NK) cells and regulate the development and differentiation of dendritic cells. IL7 has also been reported as a regulator of the development of central nervous system and myogenesis and skeletal muscle cell migration (PMID: 29663382; 29655570; 29449560)
Synonyms
IL 7, IL7, IL-7, interleukin 7