4EBP1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 13988-1-AP

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Freight/Packing

Con: 15 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
eukaryotic translation initiation factor 4E binding protein 1

Calculated molecular weight:
118aa,12 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EIF4EBP1

Synonyms
EIF4EBP1, 4EBP1, PHAS I, eIF4E binding protein 1, 4E BP1
Background

Eukaryotic translation initiation factor 4E-binding protein 1(EIF4EBP1), is a member of 4E-BPs family, which regulate the translation of a subset of mRNAs by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation facotrs to form the complex and then initiates cap-dependent translation. It also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of EIF4EP1, alpha, beta and gamma.


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