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A2BP1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22647-1-AP

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Con: 40 μg/150 μl

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Tested Applications

Applications:
IP, IHC, IF, ELISA
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A2BP1 Antibody IF mouse brain tissue 22647-1-AP

Immunofluorescent analysis of ( 4% PFA) fixed mouse brain tissue using 22647-1-AP (A2BP1 antibody) at dilution of 1:50 and Alexa Fluor 488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)

A2BP1 Antibody IF mouse brain tissue 22647-1-AP

Immunofluorescent analysis of ( 4% PFA) fixed mouse brain tissue using 22647-1-AP (A2BP1 antibody) at dilution of 1:50 and Alexa Fluor 488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)

A2BP1 Antibody IP mouse brain tissue 22647-1-AP

IP Result of anti-A2BP1 (IP:22647-1-AP, 4ug; Detection:22647-1-AP 1:500) with mouse brain tissue lysate 4000ug.

A2BP1 Antibody IHC mouse brain tissue 22647-1-AP

Immunohistochemistry of paraffin-embedded mouse brain tissue slide using 22647-1-AP( A2BP1 Antibody) at dilution of 1:200 (under 10x lens).

Species specificity:
human, mouse
Positive IP detected in:
mouse brain tissue
Positive IHC detected in:
mouse brain tissue, human brain tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in:
mouse brain tissue
Recommended dilution:
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Protocols

Product-specific protocols

Standard Protocols

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
A2BP1 fusion protein Ag18527
Full name:
ataxin 2-binding protein 1
Calculated molecular weight:
395aa,42 kDa
Observed molecular weight:
45-50 kDa
GenBank accession number:
BC113691
Gene ID (NCBI):
54715
Gene symbol
A2BP1
Synonyms
A2BP, A2BP1, ataxin 2 binding protein 1, Fox 1 homolog A, FOX1, HRNBP1, RBFOX1

Background

A2BP1, also named as FOX1 and HRNBP1, contains one RRM (RNA recognition motif) domain. A2BP1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. A2BP1 and ataxin-2 are both localized in the trans-Golgi network. This is a rabbit polyclonal antibody raised against the N terminus of human A2BP1.


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